5. Indications are based on acute and chronic pulmonary disease and dysfunction. Option D: Theophylline is a methylxanthine bronchodilator. When administering the methylxanthine theophylline, the nurse can expect: A. The mechanisms of actions focus on relaxation, dilation and decrease in secretions. Read more about the prescription drug XANTHINE DERIVATIVES - ORAL. Medscape's clinical reference is the most authoritative and accessible point-of-care medical reference for physicians and healthcare professionals, available online and via all major mobile devices. Bronchodilators: ü Xanthines Derivatives . Bronchodilators work through their direct relaxation effect on airway smooth muscle cells. The xanthine alkaloids—caffeine, theobromine, and theophylline—are closely related compounds found in a variety of plants indigenous to several continents. Theophylline is related chemically to the natural metabolite xanthine, which is a precursor of uric acid. It is the responsibility of the Respiratory Therapist to learn about the drug class. Xanthine Derivatives (Refer to Prototype List in syllabus, pg. Hopefully, this study guide can help make that process easier for you. Cushley MJ, Holgate ST. The airway response to the inhalation of four alkyl xanthines was studied in 17 subjects with moderately severe asthma (mean FEV1 1.19 litres, 42% predicted). Study asthma - bronchodilator Xanthine drugs flashcards from georgie mair's bristol university class online, or in Brainscape's iPhone or Android app. ü Beta-Agonists . Figure 8-1 shows the general xanthine structure and the structures of theophylline (1,3-dimethylxanthine) and caffeine (1,3,7-trimethylxanthine). Begins at the specific receptor stimulated Mechanism of Action Consumer information about the medication XANTHINE DERIVATIVES - ORAL , includes side effects, drug interactions, recommended dosages, and storage information. • Relieve Bronchoconstriction • Cause bronchodilatation . 19) • Prototype Drugs: – Theophylline-Theo-dur – Aminophylline . Theophylline (dimethylxanthine) has been used to treat airway diseases for more than 80 years. We also have a guide on Adrenergic Bronchodilators that I think you will enjoy. Bronchodilators Xanthine derivatives Beta-agonists Anticholinergics Antileukotriene agents Corticosteroids Mast cell stabilizers Sympathomimetic Agents ie epi, ephedrine, isoproterenol, terbutaline. Decreased pulmonary function B. Learn faster with spaced repetition. at present, three major classes of bronchodilators, β(2)-adrenoceptor (AR) agonists, muscarinic receptor antagonists, and xanthines are available and can be used individually or in combination. With bronchodilator types being B-agonists, anticholinergic and xanthine derivatives. How Do These Drugs Work? The nurse instructs the client to limit the intake of xanthine-containing foods such as chocolate, cola, cocoa, tea, and coffee. All content is free. Bronchodilator actions of xanthine derivatives administered by inhalation in asthma. The topic of Xanthine Medications will likely be covered in the Pharmacology courses of your school program. ... Bronchodilators: Beta-Agonists Mechanism of Action. BRONCHODILATOR CLASSIFICATIONS. Specific xanthine agents. Because of their methyl attachments, these agents are often referred to as methylxanthines. Is a precursor of uric acid to as methylxanthines and decrease in secretions xanthine bronchodilator mechanism. Uric acid with bronchodilator types being B-agonists, anticholinergic and xanthine derivatives their attachments. 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